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Oral antibiotic efficacy
Antibiotics are very popular in the disease treatment. Lots of problems such as toxicity, allergy, secondary infection and the change of germ anti-drug capability happened in the treatment process. Rational application of antibiotics will significantly increases the efficiency and lowers the untoward effects. The core of rational medicine is personalized medication. Pharmacogenomics adopts the gene testing such as some disease related single nucleotide polymorphism (SNP) and further the testing for the variation of SNP in the population of sensitivity and resistivity, and then instruct the clinical use of antibiotics. Personalized dose and rational combination of medicines are easily to make.
Oral intake of antibiotics is the common administration. The efficiency is mainly related to the bioavailability of oral preparation. The variations of some genes in the intestine show different effects on the antibiotics biotransformation and activate exocytosis of medicine absorbed. If personal genotypes are testing and the genotypes are significantly related to the healing efficiency, these information can be used for doctors in the medication by these personal variations, which promotes the bioavailability, lower the probably of blind medication and the risk of human body jeopardizing human body, the changing of bacterial drug resistance and costs in the treatment.
The product contains the personal genetic testing results and rational advises in antibiotics usingŁ¬for example, genetic testing of oral antibiotics efficiency of cefazoline, cefoperazone sodium, azithromycin and so on. |
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